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Search Results for " myelin oligodendrocyte glycoprotein "

Targets Recommended: Others

14

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7657	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat 髓鞘少突胶质细胞糖蛋白,MOG (35-55)	Others	Others
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) 是中枢神经鞘的一个次要成分。它能诱导强效的 T 细胞和 B 细胞反应，同时是高度脑源性的。它能够引发复发缓解性神经系统疾病，伴有广泛的斑块样脱髓鞘。
T7657L	MOG peptide (35-55) , mouse, rat acetate Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate,MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base)	Others	Others
	Myelin Oligodendrocyte Glycoprotein (MOG) peptide (35-55) , mouse, rat acetate 是MOG peptide (35-55)衍生物。 MOG peptide (35-55)是髓鞘少突胶质细胞糖蛋白 (MOG) 免疫原肽的一部分。MOG peptide (35-55) 特异性作用于 CD4+ T 细胞，能够给诱导实验性自身免疫性脑脊髓炎 (EAE) 动物模型。MOG peptide (35-55) , mouse, rat acetate(149635-73-4 Free base)是MOG peptide (35-55)衍生物。 MOG peptide (35-55)是髓鞘少突胶质细胞糖蛋白 (MOG) 免疫原肽的一部分，可用于研究与免疫相关的疾病。
T83695	MOG Peptide (human, bovine) acetate Myelin Oligodendrocyte Glycoprotein Peptide
	Myelin Oligodendrocyte Glycoprotein (MOG) peptide 是 MOG 的一种内源性肽段截取，存在于髓鞘的细胞外表面。当与抗原血清型HLA-DR2结合时，MOG peptide 在通过中脑动脉阻塞（MCAO）诱导的缺血性中风模型中，能减少皮层和纹状体梗死体积，降低管-角转测试中的感觉运动障碍，增加对新奇气味的探索时间，以及增加雌性（但不是雄性）小鼠对笼伴侣发出的呼叫持续时间。
T81733	Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse MOG (40-54)
	Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse (MOG (40-54)) 是一种与 H-2Db 关联的CD8+T细胞自身抗原表位，来源于髓鞘少突神经胶质细胞糖蛋白 (MOG)。
T78542	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate MOG (35-55) (acetate)
	Myelin Oligodendrocyte GlycoproteinPeptide (35-55), mouse, rat (MOG (35-55)) acetate 是一中枢神经系统髓鞘的非主要成分，它显示出致脑炎活性，并能诱导 T 细胞增殖。此外，MOG (35-55) acetate 能够诱导 Th1 细胞因子反应，并促使相对高水平的 IgG 抗体生成。它也可能引起复发性和缓解性的神经系统疾病，并伴随广泛的斑块样脱髓鞘现象。
T78541	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA MOG (35-55) (TFA)
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA 是一种具有致脑炎活性的化合物，能够诱导 T 细胞增殖和 Th1 细胞因子反应，并促使产生相对较高水平的 IgG 抗体。此化合物作为中枢神经鞘的次要成分，可触发带有广泛斑块样脱髓鞘的复发缓解性神经系统疾病。
TP1091	MOG (35-55) (TFA) (149635-73-4 free base) MOG (35-55) (TFA),Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (TFA) is a minor component of CNS myelin.
T39671	MOG (89-113), human
	MOG (89-113), human is a peptide fragment of human myelin oligodendrocyte glycoprotein.
T81771	MOG peptide (79-96) rat
	MOG肽(79-96)大鼠是一种髓鞘少突胶质糖蛋白，能够诱导脑炎。
T78031	MOG peptide (35-55)
	MOG peptide (35-55) 是一段特定的髓鞘少突胶质细胞糖蛋白 (MOG) 免疫原肽的35至55氨基酸序列。该肽段具有针对CD4+T细胞的特异性活性，并可用于诱导实验性自身免疫性脑脊髓炎 (EAE) 的动物模型。
T81772	MOG (92–106), mouse, rat
	MOG (92–106), mouse, rat 是一种来自小鼠/大鼠髓磷脂少突胶质细胞糖蛋白的生物活性肽，包含氨基酸片段92至106。在MOG (92–106) 诱导的实验性自身免疫性脑脊髓炎模型中，小鼠会对次级髓磷脂抗原呈现出广泛的B细胞反应性，尽管T细胞反应较弱。该肽段在SJL小鼠、DA大鼠以及恒河猴中均可诱导严重的脑炎。
T83690	[Leu144, Arg147]-PLP (139-151) TFA [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
	[Leu144,Arg147]-PLP (139-151)是髓鞘脂蛋白(PLP)的一种突变肽段，包含位于144和147位置的色氨酸到亮氨酸以及组氨酸到精氨酸的替换。使用[Leu144, Arg147]-PLP (139-151)（50 µg）乳化于完全弗氏佐剂(CFA)免疫后，能增加小鼠脾脏中的IL-4水平。它在体外抑制Th1细胞激活，但在体内不抑制，其中它诱导调节性T细胞的产生。用[Leu144, Arg147]-PLP (139-151)预免疫可以延迟由脑炎肽PLP (178-191)、髓磷脂少突细胞蛋白(MOG) (92-106)或髓鞘基础蛋白(MBP)在小鼠中诱导的实验性自身免疫性脑炎(EAE)的发病。
T83910	S1PL-IN-31 Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31
	S1PL-IN-31是一种鞘氨醇-1-磷酸(S1P)裂解酶的抑制剂(IC50 = 210 nM)，同时也是Smoothened(Smo)受体的对抗剂(IC50 = 440 nM)。在体内，S1PL-IN-31 (每天2 mg/kg)能够防止实验性自身免疫性脑炎(EAE)模型大鼠中，由髓鞘少突胶质细胞糖蛋白(MOG)肽段MOG29-152诱发的颈部及胸部淋巴细胞渗透和神经肌肉虚弱。该化合物降低了大鼠的淋巴细胞总数及CD4+ T细胞、CD8+ T细胞和B细胞的水平。S1PL-IN-31 (每天3及10 mg/kg剂量)在雄性和雌性大鼠心脏和淋巴结中增加了S1P水平，并且在雌性大鼠中降低了心率。
T38106	JC-171
	JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activation and IL-1β production in primary macrophages dose dependently[1]. ...

化合物

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat

Cat.No: T7657

Synonym: 髓鞘少突胶质细胞糖蛋白,MOG (35-55)

Target: Others

MOG peptide (35-55) , mouse, rat acetate

Cat.No: T7657L

Synonym: Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate,MOG peptide (35-55) , mouse, rat acetate (149635-73-4 Free base)

Target: Others

MOG Peptide (human, bovine) acetate

Cat.No: T83695

Synonym: Myelin Oligodendrocyte Glycoprotein Peptide

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

Cat.No: T81733

Synonym: MOG (40-54)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate

Cat.No: T78542

Synonym: MOG (35-55) (acetate)

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA

Cat.No: T78541

Synonym: MOG (35-55) (TFA)

MOG (35-55) (TFA) (149635-73-4 free base)

Cat.No: TP1091

Synonym: MOG (35-55) (TFA),Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA

MOG (89-113), human

Cat.No: T39671

MOG peptide (79-96) rat

Cat.No: T81771

MOG peptide (35-55)

Cat.No: T78031

MOG (92–106), mouse, rat

Cat.No: T81772

[Leu144, Arg147]-PLP (139-151) TFA

Cat.No: T83690

Synonym: [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

Cat.No: T83910

Synonym: Sphingosine-1-Phosphate Lyase Inhibitor 31,S1PL Inhibitor 31,S1P Lyase Inhibitor 31

Cat.No: T38106

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02085	OMGP Protein, Human, Recombinant (aa 1-416, His) OMGP,oligodendrocyte myelin glycoprote...	Human	HEK293
	Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG /...
TMPY-02126	OMGP Protein, Mouse, Recombinant (aa 1-245, His) oligodendrocyte myelin glycoprotein	Mouse	HEK293
	Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG /...
TMPY-02565	MOG Protein, Mouse, Recombinant (aa 30-149, His) B230317G11Rik,myelin oligodendrocyte g...	Mouse	E. coli
	Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions...
TMPY-02086	OMGP Protein, Human, Recombinant (aa 1-420, His) OMGP,oligodendrocyte myelin glycoprote...	Human	HEK293
	Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG /...
TMPY-00994	MOG Protein, Human, Recombinant (aa 30-149, His) NRCLP7,BTNL11,myelin oligodendrocyte g...	Human	E. coli
	Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions...
TMPJ-00295	NgR Protein, Mouse, Recombinant (hFc) Nogo-66 Receptor,Nogo Receptor,NgR,RTN4R,NOGOR,Reticulon-4 R...	Mouse	Human Cells
	Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop...
TMPJ-00277	NgR3 Protein, Human, Recombinant (His) NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Like 1,NgR3,...	Human	Human Cells
	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ...
TMPY-01056	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) NOGOR,reticulon 4 receptor,NGR	Human	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Leucine-rich) repeats. RTN4R is expressed predominantly in neurons and their axons in the central nervous systems (CNS). As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (OMG), RTN4R mediates axonal growth...
TMPY-01163	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) Rtn4r,NgR,NgR1,reticulon 4 receptor,NOGOR	Mouse	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Leucine-rich) repeats. RTN4R is expressed predominantly in neurons and their axons in the central nervous systems (CNS). As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (OMG), RTN4R mediates axonal growth...
TMPY-01221	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) NgR1,reticulon 4 receptor,NgR,Rtn4r,NOGOR	Mouse	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Leucine-rich) repeats. RTN4R is expressed predominantly in neurons and their axons in the central nervous systems (CNS). As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (OMG), RTN4R mediates axonal growth...
TMPY-03144	Nogo Receptor/RTN4R Protein, Human, Recombinant (His) NGR,reticulon 4 receptor,NOGOR	Human	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Leucine-rich) repeats. RTN4R is expressed predominantly in neurons and their axons in the central nervous systems (CNS). As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (OMG), RTN4R mediates axonal growth...

重组蛋白

OMGP Protein, Human, Recombinant (aa 1-416, His)

Cat.No: TMPY-02085

Species: Human

Expression System: HEK293

OMGP Protein, Mouse, Recombinant (aa 1-245, His)

Cat.No: TMPY-02126

Species: Mouse

Expression System: HEK293

MOG Protein, Mouse, Recombinant (aa 30-149, His)

Cat.No: TMPY-02565

Species: Mouse

Expression System: E. coli

OMGP Protein, Human, Recombinant (aa 1-420, His)

Cat.No: TMPY-02086

Species: Human

Expression System: HEK293

MOG Protein, Human, Recombinant (aa 30-149, His)

Cat.No: TMPY-00994

Species: Human

Expression System: E. coli

NgR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00295

Species: Mouse

Expression System: Human Cells

NgR3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00277

Species: Human

Expression System: Human Cells

Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01056

Species: Human

Expression System: HEK293

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01163

Species: Mouse

Expression System: HEK293

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01221

Species: Mouse

Expression System: HEK293

Nogo Receptor/RTN4R Protein, Human, Recombinant (His)

Cat.No: TMPY-03144

Species: Human

Expression System: HEK293

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